Other diseases that might be connected to oxidative stress


Autoimmune diseases

What are autoimmune diseases?

If someone is suffering from autoimmune diseases the bodies own immune system attacks our own body’s cells. For example rheumatoid arthritis, hashimoto’s, lupus, crohn’s disease and more.

The cause of those diseases is mostly unknown, which is why the therapy is only symptomatic.

Bashir S, Harris G, Denman MA, Blake DR, Winyard PG. Oxidative DNA damage and cellular sensitivity to oxidative stress in human autoimmune diseases. Annals of the rheumatic diseases. 1993 Sep 1;52(9):659-66.

Alzoghaibi MA. Concepts of oxidative stress and antioxidant defense in Crohn’s disease. World journal of gastroenterology: WJG. 2013 Oct 21;19(39):6540.
Chronic Fatigue Syndrome

CFS causes severe exhaustion of the body and the mind with involvement of the immune system, the autonomous nerve system (dysautonomia) and many other limitations.

CFS means a huge challenge for the medical world because there are no typical lab parameters and it is mainly diagnosed through exclusion of other causes.

Diagnostic criteria:

A clinical case definition and guidelines for medical practitioners
An overview of the canadian consensus document
http://sacfs.asn.au/download/consensus_overview_me_cfs.pdf

There is no clear cause but some CFS patients suffer from neuro-immunological disturbances.

Therapeutic approaches are limited. The most important part is to improve quality of life of CSF patients.

Kennedy G, Spence VA, McLaren M, Hill A, Underwood C, Belch JJ. Oxidative stress levels are raised in chronic fatigue syndrome and are associated with clinical symptoms. Free radical biology and medicine. 2005 Sep 1;39(5):584-9.