Most of the discussed correlations are based on oxidative stress. There are many publications about the relation between some of the later mentioned diseases and their relationship to oxidative stress which does not necessarily and certainly not always mean that this can be attributed to the cervical spine instability. It is also not clear whether oxidative stress causes those diseases or is a consequence of them. Further aggravating is the fact that most of the later discussed diseases are unclear in their cause.
During my extensive literature search I found possible connections between many different conditions and oxidative stress. For example: different cancer, autism, ALS, MS, Alzheimer, Parkinson, autoimmun diseases, irritable bowel… I would therefore like to distance myself from the opinion that cervical spine instabilities lead to all those diseases.
Oxidative stress describes a mechanism which plays a role in different body regulation mechanisms.
Oxidative Stess / Nitrostative Stress / Secondary mitochondrial cytopathy
What is oxidative/nitrostative stress?
If there are excessive oxygen compounds in our body this metabolic situation is called oxidative stress which can lead to mitochondrial dysfunction and to the damage of structures throughout our cells like DNA.
On the other side if there are too many reactive nitrogen compounds it is called nitrostative stress. Nitrostress can lead to apoptosis (natural cell death).
To diagnose oxidative or nitrostative stress we use different lab parameters.
NO in breathing air
Citrulline in urine
Furthermore some trace elements, vitamines and other substances which are involved in protecting from oxidative stress or occur as a consequence from it can be measrued.
Alpha lipoic acid
Coenzyme Q 10
Vitamin B1 and B6
Zinc, Copper, Manganese, Selenium
Lactate / Pyruvate
More information about the therapy of secondary mitochondropathy see here.
Secondary mitochondropathy lead to oxidative and nitrostative stress and could be acquired throughout the life (antibiotics, chemicals and other environmental influences).
Only primary mitochondrial dysfunctions which are severe genetic conditions are recognized in medicine.